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Slimming Capsules ??  An Anti Obesity Drive

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems.^[1][2] People are considered obese when their body mass index(BMI), a measurement obtained by dividing a person's weight in kilograms by the square of the person's height in metres, exceeds 30 kg/m².^[3]

Obesity increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis.^[2] Obesity is most commonly caused by a combination of excessive food energy intake, lack of physical activity, and genetic susceptibility, although a few cases are caused primarily by genes, endocrine disorders, medications orpsychiatric illness. Evidence to support the view that some obese people eat little yet gain weight due to a slow metabolism is limited; on average obese people have a greater energy expenditure than their thin counterparts due to the energy required to maintain an increased body mass.^[4][5]

Dieting and physical exercise are the mainstays of treatment for obesity. Diet quality can be improved by reducing the consumption of energy-dense foods such as those high in fat and sugars, and by increasing the intake of dietary fiber. Anti-obesity drugs may be taken to reduce appetite or inhibit fat absorption together with a suitable diet. If diet, exercise and medication are not effective, a gastric balloon may assist with weight loss, or surgery may be performed to reduce stomach volume and/or bowel length, leading to earliersatiation and reduced ability to absorb nutrients from food.^[6][7]

Obesity is a leading preventable cause of death worldwide, with increasing prevalence in adults and children, and authorities view it as one of the most serious public health problems of the 21st century.^[8] Obesity is stigmatized in much of the modern world (particularly in the Western world), though it was widely perceived as a symbol of wealth and fertility at other times in history, and still is in some parts of the world.^[2][9] In 2013, the American Medical Association classified obesity as a disease. 

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Ingerdients in VESTIGE  Slimming Capsules - 

What is Hoodia Gordonii?

• One of thirteen species which belong to the Hoodia plant family
• Naturally found in very dry, hot plains and rocky areas, such as those in South Africa
• For generations it has been used by South African Tribes as a tool during long hunting trips into the desert regions. By consuming Hoodia Gordonii prior to their hunt, they have been known to eliminate their hunger for days at a time

What does Hoodia Gordonii do?

• Eliminates the craving for food and makes you eat less, thereby reducing your weight
• Contains ‘P57’ molecule, which tells the Hypothalamus in the brain that you are full even if you aren’t full
• Works as a natural appetite suppressant

What is Garcenia Combogia?

• A fruit indigenous to India and Thailand
• Can be helpful in controlling appetite
• Triggers fatty acid oxidation in the liver
• Acts as an active appetite suppressant

What does Garcenia Combogia do?

• Promotes fat oxidation
• Increases serotonin release and its availability in brain
• Normalizes lipid profiles and reduces serum leptin levels in overweight people
• Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers

What does Garcenia Combogia do?

• Reduces both the volume and acidity of gastric juice
• Enhances metabolism
• Improves energy levels and strengthens the immune system
• The active constituent Hydroxycitric acid or HCA reduces the body’s ability to form adipose(fatty) tissue during times of overeating
• Increases glycogen in the liver, which sends a message to the brain indicating satiety, and in turn reduces appetite

What is Coleus Forskohlii?

• An ancient Ayurvedic plant and member of the mint and lavender family, which grows in the mountains of Asia
• Since ancient times, plants of the Coleus species have been used as an herbal medicine to treat various disorders of the cardiovascular, respiratory, gastrointestinal, and central nervous systems

What is Coleus Forskohlii?

• The active ingredient in coleus is forskolin, which plays a major role in a variety of important cellular functions, including inhibiting histamine release, relaxing muscles, increasing thyroid function, and increasing fat- burning activity
• Forskolin initiates a series of chemical reactions that cause fat cells to basically release their energy and melt away
• Forskolin is the only plant derived compound known to directly stimulate the enzyme, adenlylate cyclase, and in turn, stimulates cellular cyclic AMP which boosts our metabolism

What does Coleus Forskohlii do?

• An ancient Ayurvedic plant and member of the mint and lavender family, which grows in the mountains of Asia
• Since ancient times, plants of the Coleus species have been used as an herbal medicine to treat various disorders of the cardiovascular, respiratory, gastrointestinal, and central nervous systems
• The active ingredient in coleus is forskolin, which plays a major role in a variety of important cellular functions, including inhibiting histamine release, relaxing muscles, increasing thyroid function, and increasing fat- burning activity
• Forskolin initiates a series of chemical reactions that cause fat cells to basically release their energy and melt away
• Forskolin is the only plant derived compound known to directly stimulate the enzyme, adenlylate cyclase, and in turn, stimulates cellular cyclic AMP which boosts our metabolism

What does Coleus Forskohlii do?

• Increases the body's metabolism, to burn more calories
• Increases utilization of body fat
• Breaks down adipose(fat) tissue and prevents production of fatty tissue
• Mildly stimulates the metabolism by increasing thyroid hormones and increases the secretion of insulin
• Stimulates digestion and is thought to assist in the absorption of nutrients in the small intestine
• Conditions such as hypothyroidism, eczema, psoriasis are also improved by using coleus; largely due to its ability to increase cyclic AMP
• Coleus increases stroke volume, which is the amount of blood pumped in each heart beat, and reduces the risk of blood clots
• Coleus lowers high blood pressure by acting to relax the arterial walls

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PCOS & its Natural Treatment

What is polycystic ovarian syndrome (PCOS)?

Polycystic ovarian syndrome, or PCOS, is a condition in which a woman’s levels of the sex hormones estrogen and progesterone are out of balance. This leads to the growth of ovarian cysts (benign masses on the ovaries). PCOS can cause problems with a women’s menstrual cycle, fertility, cardiac function, and appearance.

What causes PCOS? 

While the exact cause of PCOS is unknown, doctors believe that hormonal imbalances and genetics play a role. Women are more likely to develop PCOS if their mother or sister also has the condition.

Overproduction of the hormone androgen may be another contributing factor. Androgen is a male sex hormone that women’s bodies also produce. Women with PCOS often produce higher-than-normal levels of androgen. This can affect the development and release of eggs during ovulation. Excess insulin (a hormone that helps convert sugars and starches into energy) may cause high androgen levels.

Symptoms of PCOS

Symptoms of PCOS typically start soon after a woman begins to menstruate. The type and severity of symptoms varies from person to person. The most common characteristic of PCOS is irregular menstrual periods.

Because PCOS is marked by a decrease in female sex hormones, this condition may cause women to develop certain male characteristics, such as:

·         excess hair on the face, chest, stomach, thumbs, or toes

·         decrease in breast size

·         deeper voice

·         thin hair

·         Other symptoms include:

·         acne

·         weight gain

·         pelvic pain

·         anxiety or depression

·         infertility

While not symptoms of the disease, many women with PCOS have other concurrent health problems, such as diabetes, hypertension, and high cholesterol. These are linked to the weight gain typical in PCOS patients.

What are the potential complications of PCOS?

Women with PCOS have a higher risk of developing:

hypertension (high blood pressure)

high cholesterol

anxiety and depression

sleep apnea (when a person stops breathing periodically during sleep)

endometrial cancer (cancer caused by thickening of the lining of the uterus)

heart attack

diabetes

breast cancer

PCOS Natural Treatment

Flaxseed can also be used to combat PCOS as it helps decrease androgen levels. It contains lignans that increase the production of sex hormone binding globulin (SHBG) that binds testosterone in the blood, thereby preventing it from wreaking havoc in the body.

Plus, being high in fiber, flaxseed helps slow down glucose metabolism and lower cholesterol levels. The omega-3 fatty acids in this superfood also reduce inflammation, lower blood pressure and reduce the risk of chronic diseases like heart disease.

-Mix one or two tablespoons of freshly ground flaxseeds in a glass of water. Drink it daily for a few months or until you are satisfied with the results.

-Also include ground flaxseeds in your diet regularly by adding it to your smoothies, soups and salads.

Reishi

(Ganoderma lucidum)Ganoderma lucidum (Reishi, Ling Zhi) – In a research study exploring the anti-androgenic effects of 20 species of mushrooms, reishi mushrooms had the strongest action in inhibiting testosterone. That study found that reishi mushrooms significantly reduced levels of 5-alpha reductase, preventing conversion of testosterone into the more potent DHT. High levels of DHT are a risk factor for conditions such as benign prostatatic hypertrophy (BPH), acne, and baldness. (Grant & Ramasamy 2012)

NONI : DRINK A SUPERFOOD TONIC IN THE MORNING:

I absolutely love noni juice as a daily tonic! Noni is a super powerful healing tonic used for thousands of years. Noni has been esteemed for its anti -inflammatory properties, boost of energy levels, aiding in cardiovascular health, immunity boost, anti fungal properties and promotes healthy liver function! I measure one shot of noni juice and pour into a large glass of water first thing in the morning. Drinking an antioxidant-rich drink first thing in the morning is a great start to the day!

CALCIUM : We all need a little bit of sunshine in our lives, not just because it makes us feel so much better and puts a spring in our step. Exposure to the sun helps our bodies make Vitamin D, a much-needed vitamin in any PCOS Diet.

Vitamin D is important for insulin resistance, breast health, mood and weight loss. And here’s the kicker: most women with PCOS are deficient in Vitamin D (83% to be exact).

So, what’s the deal with calcium? Well, Vitamin D is needed for Calcium to absorbed by the body so if your Vitamin D levels are low, chances are you’re also in need of a Calcium boost. Calcium is also important in follicle maturation and egg development.

ALOE VERA : 

Aloe Vera is one of those herbs that are responsible for a good health of a person. Be it in the form of juice or gel or even any other supplement, Aloe Vera works effectively when it comes to polycystic ovary syndrome as well. Having fresh Aloe Vera juice early in the morning on an empty stomach has great advantages.

Aloe Vera may be a potential herb in treating Polycystic Ovarian Syndrome by enhancing the reductions of plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol or by restoring the ovarian steroid status. According to the study of PCOS was induced in Charles Foster female rats by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days), AVG treated PCOS rats exhibited significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol. The gel treatment also caused reversion of abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities, bringing them to normal. Other study also indicated that Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity. This can be attributed to phyto-components present in the extract.

Spirulina is a Complete Protein Source

Spirulina and Blue Green Algae Spirulina  is a blue-green, one-celled form of algae that thrives in warm, alkaline fresh bodies of water such as lakes and ponds  It made up of 55-70% protein which makes it the highest food source of protein in the world.  It is a rich source of minerals and the antioxidant beta-carotene as well as the essential fatty acid gamma linolenic acid (GLA). Both spirulina and blue green algae are  rich sources of chlorophyll.  When we add it to our PCOS diet, our body uses the chlorophyll to cleanse our blood and it protects our DNA from aging. You can add these algaes to your diet with a green food powder.  I believe in this nutrient so much that I added it to my store (and my morning smoothies).  Check out PCOS Diva Power Greens. | Read More on PCOS Diva

This green super food is a complete protein source, as it contains all the amino acids necessary to qualify as a complete protein source. Protein content is 50-70% of its total dry weight. There is a variation in percentage of protein content dependent on time of harvest in relation to daylight. It contains the most protein when harvested in the early daylight (interesting!).

Whole Food Spirulina Contains a Wide Variety of Vitamins and Minerals
As we all know a whole food diet is essential to healthy fertility. Spirulina provides a wide variety of vitamins and minerals, all of which are easily utilized by the body. Spirulina is an easy way to boost your nutritional intake daily!

Vitamins: A, D, E, K, Thiamin, Riboflavin, Niacin, B6, B12, Folate and Pantothenic Acid.

Minerals: Potassium, calcium, zinc, magnesium, manganese, selenium, iron, copper, and phosphorus. Because spirulina grows in fresh water, rather than salt water like seaweed, it contains a relatively low amount of sodium.

Antioxidant Content May Improve Egg & Sperm Health, Prevent Preeclampsia
Many of the vitamins and minerals in spirulina are antixoidants, which have been shown to protect the body from free radical damage. Oxidative damage due to free radicals have been shown to contribute to fertility issues such as luteal phase defect, poor egg and sperm health, as well as lowered overall immunity and health.

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Confession of a Vestige Product User

Confessions from a Vestige User

This lady is a teacher. One day became very sick and then was diagnosed with lump on the psyatic nerves due to which she was totally bedridden. 

After she started using the products like Noni, Flax oil, Spirulina and Ganoderma she started recovering and could start her normal working again. 

L Arginine - What is it?

L Arginine - What is it?

L-arginine is a chemical building block called “an amino acid.” It is obtained from the diet and is necessary for the body to make proteins. L-arginine is found in red meat, poultry, fish, and dairy products. It can also be made in a laboratory and used as medicine.

L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. L-arginine is also used for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), and male infertility.

Some people use L-arginine for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, boosting the immune system, and preventing inflammation of the digestive tract in premature infants.

L-arginine is used in combination with a number of over-the-counter and prescription medications for various conditions. For example, L-arginine is used along with ibuprofen for migraine headaches; with conventional chemotherapy drugs for treating breast cancer; with other amino acids for treating weight loss in people with AIDS; and with fish oil and other supplements for reducing infections, improving wound healing, and shortening recovery time after surgery.

Some people apply L-arginine to the skin to speed wound healing and for increasing blood flow to cold hands and feet, especially in people with diabetes. It is also used as a cream for sexual problems in both men and women.

How effective is it?

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

The effectiveness ratings for L-ARGININE are as follows:

Possibly effective for...

• Improving recovery after surgery. Taking L-arginine with ribonucleic acid (RNA) and eicosapentaenoic acid (EPA) before surgery or afterwards seems to help reduce the recovery time, reduce the number of infections, and improve wound healing after surgery.
• Congestive heart failure. Taking L-arginine along with usual treatment seems to help eliminate extra fluids that are a problem in congestive heart failure. But taking L-arginine doesn’t always improve exercise tolerance or quality of life. L-arginine should not be used instead of the usual treatments ordered by a healthcare provider.
• Chest pain associated with coronary artery disease (angina pectoris). Taking L-arginine seems to decrease symptoms and improve exercise tolerance and quality of life in people with angina. But L-arginine doesn’t seem to improve the disease itself.
• Bladder inflammation. Taking L-arginine seems to improve symptoms, but it may take up to three months of treatment to see improvement.
• Wasting and weight loss in people with HIV/AIDS, when used with hydroxymethylbutyrate (HMB) and glutamine. This combination seems to increase body weight, particularly lean body mass, and improve the immune system.
• Preventing loss of effect of nitroglycerin in people with angina pectoris.
• Problems with erections of the penis (erectile dysfunction).
• Improving kidney function in kidney transplant patients taking cyclosporine.
• Preventing inflammation of the digestive tract in premature infants.
• Cramping pain and weakness in the legs associated with blocked arteries (intermittent claudication).

Possibly ineffective for...

• Heart attack. Taking L-arginine does not seem to help prevent a heart attack. It also doesn’t seem to be beneficial for treating a heart attack after it has occurred. In fact, there is concern that L-arginine might be harmful for people after a recent heart attack. Don't take L-arginine if you have had a recent heart attack.
• Pre-eclampsia, an increase in blood pressure during pregnancy. Taking L-arginine doesn't seem to lower diastolic blood pressure (the second number) in women with pre-eclampsia in their 28th to 36th week of pregnancy.

Insufficient evidence to rate effectiveness for...

• Migraine headache. Taking L-arginine by mouth along with the painkiller ibuprofen seems to be effective for treating migraine headache. This combination sometimes starts to work within 30 minutes. But it’s hard to know how much of the pain relief is due to L-arginine, since ibuprofen can relieve migraine pain on its own.
• Decreased mental function in the elderly (senile dementia). Limited research suggests that L-arginine might improve senile dementia.
• Improving healing of diabetic foot ulcers. There is interest in using L-arginine for preventing diabetic foot ulcers. Applying L-arginine to the feet seems to improve circulation in people with diabetes, which might be helpful in preventing ulcers. But if there is already an ulcer on the foot, injecting L-arginine under the skin near the ulcer doesn’t seem to shorten healing time by much or lower the chance of needing an amputation in the future.
• High blood pressure. There is some evidence that taking L-arginine can slightly lower blood pressure in healthy people and in people with type 2 diabetes who have mild high blood pressure.
• Male infertility.
• Prevention of the common cold.
• Improving athletic performance.
• Breast cancer when used in combination with chemotherapy.
• Wound healing.
• Female sexual problems.
• Sickle cell disease.
• Improving the immune system in people with head and neck cancer.

More evidence is needed to rate L-arginine for these uses.

How does it work?

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L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances in the body.

Are there safety concerns?

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L-arginine is POSSIBLY SAFE for most people when taken appropriately by mouth short-term. It can cause some side effects such as abdominal pain, bloating, diarrhea, gout, blood abnormalities, allergies, airway inflammation, worsening of asthma, and low blood pressure.

Special precautions & warnings:

Pregnancy and breast-feeding: L-arginine is POSSIBLY SAFE when used appropriately short-term in pregnancy. Not enough is known about using L-arginine long-term in pregnancy or during breast-feeding. Stay on the safe side and avoid use.

Children: L-arginine is POSSIBLY SAFE when used by mouth in premature infants in appropriate doses. When used in high doses, L-arginine is POSSIBLY UNSAFE. Doses that are too high can cause serious side effects including death in children.

Allergies or asthma: L-arginine can cause an allergic response or make swelling in the airways worse. If you decide to take L-arginine, use it with caution.

Herpes: There is a concern that L-arginine might make herpes worse. There is some evidence that L-arginine is needed for the herpes virus to multiply.

Low blood pressure: L-arginine might lower blood pressure. This could be a problem if you already have low blood pressure.

Recent heart attack: There is a concern that L-arginine might increase the risk of death after a heart attack, especially in older people. If you have had a heart attack recently, don’t take L-arginine.

Surgery: L-arginine might affect blood pressure. There is a concern that it might interfere with blood pressure control during and after surgery. Stop taking L-arginine at least 2 weeks before a scheduled surgery.

Are there interactions with medications?

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Major

Do not take this combination.

Medications for high blood pressure (Antihypertensive drugs)

L-arginine seems to decrease blood pressure. Taking L-arginine along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others.

Medications that increase blood flow to the heart (Nitrates)

L-arginine increases blood flow. Taking L-arginine with medications that increase blood flow to the heart might increase the chance of dizziness and lightheadedness.

Some of these medications that increase blood flow to the heart include nitroglycerin (Nitro-Bid, Nitro-Dur, Nitrostat), and isosorbide (Imdur, Isordil, Sorbitrate).

Moderate

Be cautious with this combination.

Sildenafil (Viagra)

Sildenafil (Viagra) can lower blood pressure. L-arginine can also lower blood pressure. Taking sildenafil (Viagra) and L-arginine together might cause the blood pressure to go too low. Blood pressure that is too low can cause dizziness and other side effects.

Are there interactions with herbs and supplements?

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Xylitol

L-arginine can cause an organ in the body called the pancreas to release a hormone called glucagon. Glucagon comes to the rescue when blood sugar levels are too low. Glucagon makes the liver convert stored sugar to useable sugar that is released into the bloodstream. Using L-arginine along with xylitol can keep L-arginine from stimulating the pancreas to release glucagon.

Are there interactions with foods?

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There are no known interactions with foods.

What dose is used?

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The following doses have been studied in scientific research:

BY MOUTH:

• For congestive heart failure: doses range from 6-20 grams per day, as three divided doses.
• For chest pain associated with coronary artery disease (angina pectoris): 3-6 grams three times per day for up to one month.
• For preventing the loss of the effectiveness of nitroglycerin in relieving pain in people with chest pain due to coronary artery disease (angina pectoris): 700 mg four times daily.
• For organic erectile dysfunction (ED): 5 grams per day. Taking lower doses might not be effective.
• For preventing inflammation of the digestive tract in premature infants: 261 mg/kg added to oral feedings daily for the first 28 days of life.

http://www.nlm.nih.gov/medlineplus/druginfo/natural/875.html

What is Co-Enzyme Q 10 ?

COENZYME Q-10 OVERVIEW INFORMATION

CoQ10 or Coenzyme Q10 is a substance that the human body can produce naturally. CoQ10 is used by the cells to generate energy and also functions as a powerful antioxidant. Antioxidants help fight free radicals, which are believed to contribute to health problems by damaging cells and DNA.Jan




Background

CoQ10 DeficienciesMany people use coenzyme Q-10 for treating heart and blood vessel conditions such as congestive heart failure (CHF), chest pain (angina), high blood pressure, and heart problems linked to certain cancer drugs. It is also used for diabetes, gum disease(both taken by mouth and applied directly to the gums), breast cancer, Huntington’s disease, Parkinson’s disease, muscular dystrophy, increasing exercise tolerance,chronic fatigue syndrome (CFS), and Lyme disease. Some people think coenzyme Q-10 will treat hair loss related to taking warfarin (Coumadin), a medication used to slow blood clotting.Some people also think coenzyme Q-10 might help increase energy. This is because coenzyme Q-10 has a role in producing ATP, a molecule in body cells that functions like a rechargeable battery in the transfer of energy. Coenzyme Q-10 been tried for treating inherited or acquired disorders that limit energy production in the cells of the body (mitochondrial disorders), and for improving exercise performance.

Some people have also used coenzyme Q-10 for strengthening the immune systems of people with HIV/AIDS, male infertility, migraine headache, and counteractingmuscle pain sometimes caused by a group of cholesterol-lowering medications called “statins.” Coenzyme Q-10 has even been tried for increasing life span. This idea got started because coenzyme Q-10 levels are highest in the first 20 years of life. By age 80, coenzyme-Q10 levels can be lower than they were at birth. Some people thought that restoring high levels of coenzyme-Q10 late in life might cause people to live longer. The idea works in bacteria, but not in lab rats. More research is needed to see if this works in people.It’s not only time that uses up the body’s store of coenzyme Q-10. Smoking does, too.Coenzyme Q-10 was first identified in 1957. The “Q-10” refers to the chemical make-up of the substance. These days coenzyme Q-10 is used by millions of people in Japan for heart disease, especially congestive heart failure. Coenzyme Q-10 is also used extensively in Europe and Russia. Most of the coenzyme Q-10 used in the US and Canada is supplied by Japanese companies. Coenzyme Q-10 is manufactured by fermenting beets and sugar cane with special strains of yeast.

How does it work?Likely Effective for:

• Coenzyme Q-10 deficiency. Taking coenzyme Q-10 by mouth seems to improve symptoms of coenzyme Q-10 deficiency. This is a very rare condition. The symptoms include weakness, fatigue, and seizures.

• Inherited or acquired disorders that limit energy production in the cells of the body (mitochondrial disorders). Taking coenzyme Q-10 by mouth seems to reduce symptoms of mitochondrial disorders. However, improvement in symptoms is slow. Some people have to take coenzyme Q-10 for six months to get the most benefit.

Possibly Effective for:

• Age-related vision loss (age-related macular degeneration). Taking a specific product containing coenzyme Q-10, acetyl-L-carnitine, and omega-3 fatty acids (Phototrop) by mouth seems to improve vision in people with age-related vision loss.

• Congestive heart failure (CHF). Some research suggests that heart failure might be linked with low coenzyme Q-10 levels. Although most evidence shows that taking coenzyme Q-10 alone does not help treat heart failure, there is some evidence that it might be helpful when taken in combination with other heart failure medications and treatments.

• Nerve damage caused by diabetes (diabetic neuropathy). Research shows that taking coenzyme Q-10 improves nerve damage and nerve pain in people with nerve damage caused by diabetes.

• HIV/AIDS. Taking coenzyme Q-10 by mouth seems to improve immune function in people with HIV/AIDS.

• An inherited neurological disorder called Huntington’s disease. Ubiquinol, an altered form of coenzyme Q-10, has been granted “Orphan Drug Status” by the U.S. Food and Drug Administration (FDA). This gives the maker of Ubiquinol some financial incentives to study its effectiveness for Huntington’s, a condition that is so rare (affecting less than 200,000 individuals) that pharmaceutical companies might not otherwise invest in developing a drug for it. However, taking coenzyme Q-10 by mouth in doses of 600 mg daily or less does not seem to be effective for slowing the progression of Huntington’s disease.

• High blood pressure. The majority of research shows that taking coenzyme Q-10 by itself or along with other medications for treating high blood pressure seems to help lower blood pressure. However, one small study suggests that taking coenzyme Q-10 by mouth may not lower blood pressure in people that also have a condition called metabolic syndrome.

• Blood vessel complications caused by heart bypass surgery. Reduced blood supply during heart or blood vessel surgery can deprive tissue of oxygen. When blood supply returns to this tissue, the tissue can become damaged. There is some evidence that taking coenzyme Q-10 by mouth for a week before heart bypass surgery or blood vessel surgery might help to reduce tissue damage. However, not all research agrees with this finding.

• A specific type of high blood pressure. Taking coenzyme Q-10 daily appears to lower systolic blood pressure (the top number) in some people with high systolic blood pressure but normal diastolic blood pressure (the bottom number).

• Migraine headache. Taking coenzyme Q-10 by mouth seems to help prevent migraine headaches. Studies show it can decrease the frequency of headaches by about 30% and the number of days with headache-related nausea by about 45% in adults. Taking coenzyme Q-10 also appears to reduce migraine frequency in children who have low levels of coenzyme Q-10. It can take up to 3 months for significant benefit. However, coenzyme Q-10 does not seem to be effective in treating migraines once they have developed.

• An inherited muscle disorder called muscular dystrophy. Taking coenzyme Q-10 by mouth seems to improve physical performance in some people with muscular dystrophy

• Heart attack. When started within 72 hours of a heart attack and taken for one year, coenzyme Q-10 appears to lower the risk of heart-related events, including another heart attack.

• Parkinson’s disease. Some research shows that taking coenzyme Q-10 supplements might slow decline in people with early Parkinson’s disease. However, taking a coenzyme Q-10 does not seem to improve symptoms in people with mid-stage Parkinson’s disease.

• Peyronie’s disease (painful erection in men). Research shows that taking coenzyme Q-10 improves erectile function in men with painful erections.

Possibly Ineffective for:

• Alzheimer’s disease. Taking coenzyme Q-10 does not seem to improve mental function in people with Alzheimer’s disease.

• Neurodegenerative disease called ALS or Lou Gehrid’s disease. Research shows that taking coenzyme Q-10 does not slow the progression of ALS.

• Cocaine dependence. Taking a combination of coenzyme Q-10 and L-carnitine does not reduce cocaine use.

• High cholesterol. Some research shows that taking coyenzme Q-10 does not reduce total cholesterol, triglycerides, or low-density lipoprotein (LDL or “bad”) cholesterol, or increase high-density lipoprotein (HDL or “good”) cholesterol. Other research shows that taking coenzyme Q-10 by mouth alone or together with carnitine does not improve cholesterol levels. However, one study in people who can not take statin drugs shows that taking a combination of coenzyme Q-10, berberine, policosanol, red yeast rice, folic acid, and astaxanthin reduces cholesterol levels.

• Symptoms affecting polio survivors (post-polio syndrome). Research shows that taking coenzyme Q-10 does not improve muscle strength or muscle function in people with post-polio syndrome.

Likely Ineffective for:

• Athletic performance. Taking coenzyme Q-10 by mouth does not improve althetic performance in athletes or non-athletes.

Insufficient Evidence for:

• Chest pain (angina). Some early research suggests that taking coenzyme Q-10 by mouth might improve exercise tolerance in patients with angina.

• Asthma. Some early research suggests that taking a combination of coenzyme Q-10, vitamin E (alpha-tocopherol), and vitamin C in addition to conventional asthma treatment reduces the dosage of drugs needed by people with mild-to-moderate asthma.

• Breast cancer. Some research in Chinese women suggests that having low blood levels of coenzyme Q-10 is linked to an increased risk of breat cancer. There is preliminary evidence that taking coenzyme Q-10 by mouth might be helpful in advanced breast cancer when used along with surgery and conventional treatment plus other antioxidants and omega-3 and omega-6 fatty acids.

• Cancer. Research suggests that low coenzyme Q-10 levels are associated with an increased risk of skin cancer. Also, early research suggests that taking coenzyme Q-10 along with other antioxidants increases survival time by 40% in patients with terminal cancer.

• Heart toxicity caused by chemotherapy drugs. Some research suggests that taking coenzyme Q-10 by mouth may protect the heart in children and adults receiving the chemotherapy drug anthracycline. However, other research suggests that administering coenzyme Q-10 intravenously (by IV) does not provide this benefit.

• Lung disease called chronic obstructive pulmonary disease (COPD). Early research suggests that taking coenzyme Q-10 improves lung function and exercise tolerance in people with COPD.

• Cyclic vomiting syndrome. Some early research suggests that taking coenzyme Q-10 might work as well as prescription medications used to treat cyclic vomiting syndrome.

• Diabetes. Research about the effectiveness of coenzyme Q-10 for diabetes is conflicting. Some research shows that taking coenzyme Q-10 might lower blood sugar levels. However, other research has found no benefit.

• Weakend and enlarged heart (dilated cardiomyopathy). Early evidence suggests that taking coenzyme Q-10 improves heart function in children with dilated cardiomyopathy.

• Dry mouth. Early research suggests that taking coenzyme Q-10 (ubiquinol) improves dry mouth.

• Eye surgery. Research suggests that administering an eye solution containing coenzyme Q-10 and vitamin E increases the speed of nerve regeneration after cataract eye surgery

• Fibromyalgia. Some early research suggests that taking coenzyme Q-10 along with ginkgo might increase feelings of wellness and overall health, as well as reduce pain in people with fibromyalgia.

• Uncoordinated movement due to brain damage (cerebellar ataxia). Early research suggests that coenzyme Q-10 improves muscle coordination and movement in people with cerebellar ataxia.

• Rare inherited disease that causes nerve damage (Friedreich’s ataxia). Early research suggests that taking vitamin E together with coenzyme Q-10 improves coordination, posture, and movement in people with Friedreich’s ataxia.

• Hearing loss. Research suggests that taking a specific coenzyme Q-10 product (Q-TER) by mouth improves hearing in people with age-related hearing loss. However, combining coenzyme Q-10 with conventional steroid treatments does not improve hearing more than steroid treatment alone.

• Hepatitis C. Research shows that taking coenzyme Q-10 does not improve liver function in people with hepatitis C who are not responding to conventional treatment.

• A heart condition called hypertrophic cardiomyopathy. Taking coenzyme Q-10 by mouth seems to decrease the thickness of the heart wall and decrease symptoms of shortness of breath and fatigue in people with hypertrophic cardiomyopathy.

• Rare genetic disorder called Prader-Willi syndrome. Early research suggests that administering coenzyme Q-10 improves development in children with Prader-Labhart-Willi syndrome. However, it is not clear if these improvements are due to the coenzyme Q-10 or an age-related phenomenon.

• Male infertility. There is some early evidence that coenzyme Q-10 treatment can improve the movement and density of sperm in men with certain types of infertility. However, other research shows that it does not have a beneficial effect on sperm movement.

• Inherited diabetes and deafness. There is some early evidence that taking coenzyme Q-10 by mouth might prevent the progression of a rare form of diabetes that is maternally inherited.

• Gum disease. Applying coenzyme Q-10 to the gums is not effective for treating gum disease. However, there is some early evidence that taking coenzyme Q-10 by mouth might be helpful in treating gum disease.

• High blood pressure during pregnancy (pre-eclampsia). Pre-eclampsia is a condition that some women develop during pregnancy. Some research shows that women who are at risk have a lower chance of developing the condition if they take coenzyme Q-10 from week 20 of pregnancy until the baby is delivered

• Prostate cancer. Research shows that taking a combination of vitamin E, selenium, vitamin C, and coenzyme Q-10 does not improve prostate cancer.

• Kidney failure. Some early research suggests that taking coenzyme Q-10 improves kidney function in people with end-stage kidney disease. However, other research shows that taking coenzyme Q-10 does not improve kidney function.

• A muscle condition called “statin-induced myopathy.” Statins, a class of drugs used to lower cholesterol, can sometimes cause muscle pain. There is some evidence that taking coenzyme Q-10 might reduce this pain. However, not all evidence has been positive.

• Hair loss related to use of the warfarin. There is some early evidence that taking coenzyme Q-10 might be helpful for preventing hair loss caused by the blood-thinning drug, warfarin.

• Wrinkled skin. Early evidence suggests that applying a coenzyme Q-10 cream to the skin improves wrinkled skin.

• Fatigue.

• Lyme disease.

• Other conditions.

More evidence is needed to rate coenzyme Q-10 for these uses.http://www.webmd.com/vitamins-supplements/ingredientmono-938-coenzyme%20q-10.aspx?activeingredientid=938&

Coenzyme Q10 (CoQ10) is an antioxidant that is made in the human body. CoQ10 is needed for basic cell function. CoQ10 levels decrease with age and may be low in people with cancer, certain genetic disorders, diabetes, heart conditions, HIV/AIDS, muscular dystrophies, and Parkinson's disease. Some prescription drugs may also lower CoQ10 levels.

CoQ10 in the body can be increased by taking CoQ10 supplements. There is evidence that idebenone, a man-made compound similar to CoQ10, may help treat Alzheimer's disease. However, evidence is lacking to support the use of CoQ10 itself for this condition. There is some evidence to support the use of CoQ10 for high blood pressure and heart failure.

Promising uses of CoQ10 include eye disease, chest pain caused by exercise, asthma, chronic fatigue, and high cholesterol, as well as the treatment of chemotherapy side effects in children.

Evidence is conflicting for the use of CoQ10 in heart muscle problems and exercise performance. There is some negative evidence for the use of CoQ10 in the treatment of diabetes, hepatitis C, and Huntington's disease.

Your body produces less and less CoQ10 as you get older. According to theUniversity of Maryland Medical Center, deficiencies can appear in people with certain metabolic disorders. Although your body produces its own CoQ10, it can also be obtained from food. The best sources of CoQ10 are oily fish and organ meats, such as beef liver. Coenzyme Q10 can also be found in whole grains.
People with certain conditions, including diabetes, Parkinson’s disease, and heart problems tend to have low levels of CoQ10 in their bodies. Researchers don’t know if the disease causes the deficiency or if the deficiency appears first, causing cells to age faster and making disease more likely.
http://www.healthline.com/health/coq10-and-statins#CoQ10andtheHeart3

Coenzyme Q-10 (CoQ-10) is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas. It is eaten in small amounts in meats and seafood. Coenzyme Q-10 can also be made in a laboratory. It is used as medicine.

Coenzyme Q-10 is an important vitamin-like substance required for the proper function of many organs and chemical reactions in the body. It helps provide energy to cells. Coenzyme Q-10 also seems to have antioxidant activity. People with certain diseases, such as congestive heart failure, high blood pressure, periodontal disease, Parkinson’s disease, certain muscular diseases, and AIDS, might have lower levels of coenzyme Q-10.

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